Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 7/20 | 0.46 |
| ▸ | NOS1 | P29475 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.38 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.38 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | VNN1 | O95497 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL320058 | 0.82 | LOXL2 (0.59) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL30471916 | 0.82 | LOXL2 (0.59) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL19442370 | 0.81 | KDM4E (0.47) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL8224396 | 0.79 | KDM4E (0.55) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL1697126 | 0.79 | MAPT (0.64) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL910601 | 0.78 | MGLL (0.43) | MAPTGLA | |
| Hydrochloric Acid SCHEMBL3273205 | 0.77 | MAPT (0.68) | KDM4ECYP3A4MAPTPRMT6NOS1 | |
| SCHEMBL2324273 | 0.77 | HIF1A (0.54) | KDM4EMAPTMAOB | |
| SCHEMBL6807724 | 0.76 | CALM1 (0.50) | — | |
| SCHEMBL7284285 | 0.75 | LOXL2 (0.65) | KDM4ECYP3A4MAPTNOS1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0833845-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1998-04-08 | — | — | EP | disclosed |
| WO-1998008492-A1 | TRANSDERMAL DELIVERY OF PEPTIDES | NOVO NORDISK A/S (DK) | 1998-03-05 | — | — | WO | disclosed |
| WO-1997000894-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-01-09 | — | — | WO | disclosed |