Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139046 | 0.88 | ALDH1A1 (0.44) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL6375660 | 0.86 | ALDH1A1 (0.48) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL3004207 | 0.86 | ALDH1A1 (0.48) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL1748476 | 0.86 | ALDH1A1 (0.48) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL4262988 | 0.78 | MEN1 (0.43) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL3390209 | 0.75 | MAPT (0.43) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL7275618 | 0.73 | PLK1 (0.47) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL9514094 | 0.73 | ALDH1A1 (0.40) | GAAALDH1A1HSD17B10PGRPTGS1 | |
| SCHEMBL28546281 | 0.72 | KDM4E (0.45) | ALDH1A1HSD17B10MEN1KMT2ANPC1 | |
| SCHEMBL27702983 | 0.72 | KDM4E (0.45) | ALDH1A1HSD17B10MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |