Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.55 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.55 |
| ▸ | RXRA | P19793 | 1/20 | 0.40 |
| ▸ | RXRB | P28702 | 1/20 | 0.40 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7272586 | 1.00 | ITGB3 (0.55) | ITGB3ITGA2BRXRARXRBRXRG | |
| Hydrochloric Acid SCHEMBL7283833 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BF2F10MAPT | |
| Hydrochloric Acid SCHEMBL7281759 | 0.88 | ITGB3 (0.41) | ITGB3ITGA2BF2F10MAPT | |
| SCHEMBL7275237 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7282771 | 0.79 | ITGB3 (0.55) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7273934 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7274145 | 0.78 | ITGB3 (0.54) | ITGB3ITGA2BRXRARXRBRXRG | |
| SCHEMBL7285201 | 0.77 | ITGB3 (0.42) | ITGB3ITGA2BNQO2 | |
| SCHEMBL7274553 | 0.76 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 | |
| SCHEMBL7284791 | 0.76 | ITGB3 (0.57) | ITGB3ITGA2BF2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5852192-A | Cyclic urea derivatives, pharmaceutical compositions containing these compounds and processes for preparing them | DR. KARL THOMAE GMBH (DE) | 1998-12-22 | — | — | US | disclosed |
| US-5650424-A | ANTIAGGLOMERANTS USING IMIDAZOLIDINDIONES | DR. KARL THOMAE GMBH (DE) | 1997-07-22 | — | — | US | disclosed |
| EP-0503548-B1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | THOMAE GMBH DR K (DE) | 1997-06-04 | — | — | EP | disclosed |
| US-5478942-A | Antiinflammatory agents, antiagglomerants | KARL THOMAE GMBH (DE) | 1995-12-26 | — | — | US | disclosed |
| US-5276049-A | Treatment of thrombosis | DR. KARL THOMAE GMBH (DE) | 1994-01-04 | — | — | US | disclosed |
| EP-0503548-A1 | Cyclic urea derivatives, medicaments contaning them and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-09-16 | — | — | EP | disclosed |