Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | ESR1 | P03372 | 1/20 | 0.65 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP3 | P08254 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31574444 | 0.89 | HTT (0.83) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL900684 | 0.84 | ESR1 (0.75) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL5712143 | 0.84 | HTT (0.75) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL27147137 | 0.82 | PBRM1 (0.52) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL7940092 | 0.81 | CA12 (0.53) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL699850 | 0.81 | LMNA (1.00) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL18423 | 0.81 | LMNA (1.00) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL5079227 | 0.80 | MEN1 (0.76) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL3545449 | 0.79 | HTT (0.75) | HTTLMNAMAPTESR1ESR2 | |
| SCHEMBL24587796 | 0.78 | LMNA (0.50) | HTTLMNAMAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-8138257-B1 | Bis(trialkylsiloxyphenyl)-arylfluoride imide AB2 monomers, hyperbranched polymers and nanoclay composites therefrom | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2012-03-20 | — | — | US | disclosed |
| US-6639042-B1 | Organic solvent soluble | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-10-28 | — | — | US | disclosed |
| US-6512124-B1 | N-(3,5-bis(4-hydroxybenzoyl)benzene)-4-fluoroisophthalimide. Aromatic polyimides (Pls) are well known, high-performance materials with widespread applications in the aerospace and electronics industries due to their excellent thermomechanical | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE | 2003-01-28 | — | — | US | disclosed |