SCHEMBL900684

SCHEMBL900684

Nc1ccc(C(=O)c2ccc(O)cc2)cc1

nearest known ligand 0.75

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 3/20 0.75
ESR2 Q92731 3/20 0.75
HTT P42858 3/20 0.75
LMNA P02545 2/20 0.75
MAPT P10636 2/20 0.75
HPGD P15428 2/20 0.75
PKM P14618 1/20 0.75
CA14 Q9ULX7 3/20 0.65
CA3 P07451 2/20 0.65
CA6 P23280 2/20 0.65
ALDH1A1 P00352 1/20 0.65
CYP3A4 P08684 1/20 0.65
THRB P10828 1/20 0.65
ALOX15 P16050 1/20 0.65
CASP1 P29466 1/20 0.65
HIF1A Q16665 1/20 0.65
HSD17B10 Q99714 1/20 0.65
SRD5A2 P31213 1/20 0.62
MAPK1 P28482 1/20 0.60
MEN1 O00255 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL204877 0.89 CA12 (0.59) ESR1ESR2HTTLMNAMAPT
SCHEMBL62657 0.89 CA12 (0.59) ESR1ESR2HTTLMNAMAPT
SCHEMBL9097535 0.89 CA12 (0.59) ESR1ESR2HTTLMNAMAPT
Hydrochloric Acid SCHEMBL8640288 0.87 CA12 (0.57) ESR1ESR2HTTLMNAMAPT
SCHEMBL699850 0.87 LMNA (1.00) ESR1ESR2HTTLMNAMAPT
SCHEMBL18423 0.87 LMNA (1.00) ESR1ESR2HTTLMNAMAPT
SCHEMBL728490 0.84 HTT (0.65) ESR1ESR2HTTLMNAMAPT
Methane SCHEMBL6378712 0.84 LMNA (0.94) ESR1ESR2HTTLMNAMAPT
SCHEMBL7929114 0.84 LMNA (0.94) ESR1ESR2HTTLMNAMAPT
SCHEMBL29056089 0.84 LMNA (0.94) ESR1ESR2HTTLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119463112-B Polymer compound and process for producing the same 成都科成精化科技有限公司 2025-04-01 CN claimed
CN-119463112-A Polymer compound and process for producing the same 成都科成精化科技有限公司 2025-02-18 CN claimed
EP-2546258-B1 Novel phosphorus-containing compounds and their preparing process and use CHANG CHUN PLASTICS CO LTD (TW) 2015-12-16 EP claimed
EP-2546258-A1 Novel phosphorus-containing compounds and their preparing process and use Chang Chun Plastics Co., Ltd. (TW) 2013-01-16 EP claimed
US-8222441-B2 Phosphorus-containing compounds and their preparing process and use CHANG CHUN PLASTICS CO., LTD. (TW) 2012-07-17 US claimed
EP-2116549-A2 Novel phosphorus-containing compounds and their preparing process and use Chang Chun Plastics Co., Ltd. (TW) 2009-11-11 EP claimed
US-20090258997-A1 Novel phosphorus-containing compounds and their preparing process and use CHANG CHUN PLASTICS CO., LTD. 2009-10-15 US claimed
CN-119463112-B Polymer compound and process for producing the same 成都科成精化科技有限公司 2025-04-01 CN disclosed
CN-119463112-A Polymer compound and process for producing the same 成都科成精化科技有限公司 2025-02-18 CN disclosed
US-11866584-B2 High-refractive-index composition, high-refractive-index film, and method for manufacturing high-refractive-index film LG CHEM, LTD. (KR) 2024-01-09 US disclosed
US-20230355644-A1 ACTIVE INGREDIENTS AND DRUGS FOR THE THERAPY OF VIRAL DISEASES, ESPECIALLY CORONA INFECTIONS, ESPECIALLY COVID-19 CREATIVE THERAPEUTICS GMBH (DE) 2023-11-09 US disclosed
US-20230355644-A1 ACTIVE INGREDIENTS AND DRUGS FOR THE THERAPY OF VIRAL DISEASES, ESPECIALLY CORONA INFECTIONS, ESPECIALLY COVID-19 CREATIVE THERAPEUTICS GMBH (DE) 2023-11-09 US disclosed
CN-116554234-A Ferrocene-pyrazole hybrid compound as well as preparation method and application thereof 桂林医学院附属医院 2023-08-08 CN disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed
US-4820798-A Cyanate functional maleimide thermosetting composition THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
US-4820797-A ACETYLENIC COPOLYMERS THE DOW CHEMICAL COMPANY (US) 1989-04-11 US disclosed
US-4769440-A FLEXIBILITY THE DOW CHEMICAL COMPANY (US) 1988-09-06 US disclosed
US-4731426-A Polymerization product from cyanate functional maleimide THE DOW CHEMICAL COMPANY (US) 1988-03-15 US disclosed
US-4683276-A CASTING, LAMINATION, COATING THE DOW CHEMICAL COMPANY (US) 1987-07-28 US disclosed
US-4680378-A Cyanate functional maleimide and polyamine copolymer THE DOW CHEMICAL COMPANY (US) 1987-07-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230355644-A1 ACTIVE INGREDIENTS AND DRUGS FOR THE THERAPY OF VIRAL DISEASES, ESPECIALLY CORONA INFECTIONS, ESPECIALLY COVID-19 ACE, ACE2, SARS1 ESR1 2909/4885ESR2 2529/4885HTT 1074/4885
US-20090258997-A1 Novel phosphorus-containing compounds and their preparing process and use POLR2A, POLR2B, PRXL2A ESR1 154/4885ESR2 65/4885HTT 4799/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.