Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 7/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.57 |
| ▸ | F2 | P00734 | 3/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7282541 | 0.91 | ITGB3 (0.47) | ITGB3ITGA2BF2PRSS1PRSS2 | |
| SCHEMBL7276442 | 0.80 | ITGB3 (0.43) | ITGB3ITGA2BKDM4EALDH1A1GAA | |
| SCHEMBL7273353 | 0.78 | NPSR1 (0.43) | ITGB3ITGA2BALDH1A1L3MBTL1 | |
| SCHEMBL7275474 | 0.76 | ITGB3 (0.53) | ITGB3ITGA2BF2 | |
| SCHEMBL7274152 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BPRSS1PRSS2PRSS3 | |
| SCHEMBL7287750 | 0.74 | ITGB3 (0.51) | ITGB3ITGA2B | |
| Fradafiban SCHEMBL8863359 | 0.73 | ITGB3 (1.00) | ITGB3ITGA2BF2PRSS1ST14 | |
| Fradafiban SCHEMBL380350 | 0.73 | ITGB3 (1.00) | ITGB3ITGA2BF2PRSS1ST14 | |
| Fradafiban SCHEMBL7280818 | 0.72 | ITGB3 (0.98) | ITGB3ITGA2BF2PRSS1ST14 | |
| Hydrochloric Acid SCHEMBL7283354 | 0.71 | HCRTR1 (0.41) | ITGB3ITGA2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |