Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 3/20 | 0.57 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.57 |
| ▸ | F10 | P00742 | 12/20 | 0.46 |
| ▸ | PLG | P00747 | 2/20 | 0.46 |
| ▸ | PROC | P04070 | 1/20 | 0.46 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7281472 | 0.90 | ITGB3 (0.48) | ITGB3ITGA2BF10PLGPROC | |
| SCHEMBL7282732 | 0.81 | ITGB3 (0.57) | ITGB3ITGA2BF10PLGPRSS1 | |
| SCHEMBL7275474 | 0.78 | ITGB3 (0.53) | ITGB3ITGA2B | |
| SCHEMBL7287750 | 0.76 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7284924 | 0.75 | ITGB3 (0.57) | ITGB3ITGA2BF10PLGPRSS1 | |
| SCHEMBL7282733 | 0.75 | LMNA (0.39) | ITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL7282749 | 0.74 | TPSAB1 (0.43) | ITGB3ITGA2BMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7272974 | 0.73 | F10 (0.51) | ITGB3ITGA2BF10PLGPROC | |
| Fradafiban SCHEMBL8863359 | 0.73 | ITGB3 (1.00) | ITGB3ITGA2BF10PLGPRSS1 | |
| Fradafiban SCHEMBL380350 | 0.73 | ITGB3 (1.00) | ITGB3ITGA2BF10PLGPRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |