Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARD | Q03181 | 2/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.36 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7303103 | 0.91 | NPSR1 (0.39) | NPSR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL7276442 | 0.88 | ITGB3 (0.43) | NPSR1MEN1KMT2AHIF1AITGB3 | |
| SCHEMBL7284924 | 0.78 | ITGB3 (0.57) | ITGB3ITGA2BALDH1A1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL7282541 | 0.69 | ITGB3 (0.47) | MEN1KMT2AITGB3ITGA2BALDH1A1 | |
| SCHEMBL19979736 | 0.66 | ALDH1A1 (0.65) | NPSR1MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL8367716 | 0.66 | ALDH1A1 (0.70) | NPSR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL15923346 | 0.66 | ALDH1A1 (0.70) | NPSR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL7274152 | 0.65 | ITGB3 (0.57) | MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL15924182 | 0.64 | NPSR1 (0.71) | NPSR1MEN1KMT2AHIF1AALDH1A1 | |
| SCHEMBL14459998 | 0.64 | HCRTR1 (0.67) | NPSR1MEN1KMT2AHIF1AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5591769-A | PYRROLIDINE DERIVATIVES; ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1997-01-07 | — | — | US | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |