Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | KLK7 | P49862 | 3/20 | 0.43 |
| ▸ | KLK14 | Q9P0G3 | 3/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 3/20 | 0.43 |
| ▸ | CTSG | P08311 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7290454 | 1.00 | IMPDH2 (0.50) | IMPDH2PDE3BPDE3AHTTNPSR1 | |
| SCHEMBL7290836 | 0.94 | ALDH1A1 (0.47) | IMPDH2PDE3BPDE3AHTTALDH1A1 | |
| SCHEMBL372048 | 0.89 | IMPDH2 (0.58) | IMPDH2PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL15275124 | 0.88 | IMPDH2 (0.50) | IMPDH2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7291390 | 0.87 | PDE3B (0.51) | IMPDH2PDE3BPDE3AENPP1ALDH1A1 | |
| SCHEMBL7294056 | 0.87 | IMPDH2 (0.49) | IMPDH2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL29842783 | 0.86 | IMPDH2 (0.48) | IMPDH2PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL16207483 | 0.86 | IMPDH2 (0.48) | IMPDH2PDE3BPDE3AALDH1A1KDM4E | |
| SCHEMBL5650019 | 0.86 | IMPDH2 (0.48) | IMPDH2ALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL7293565 | 0.83 | IMPDH2 (0.46) | IMPDH2ALDH1A1KDM4EMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0343574-B1 | 4(1H)-quinolone derivatives | KIRIN BREWERY (JP) | 1994-07-27 | — | — | EP | disclosed |
| US-5081121-A | Cardiotonic agents | KIRIN BEER KABUSHIKI KAISHA (JP) | 1992-01-14 | — | — | US | disclosed |