SCHEMBL7285244

SCHEMBL7285244

CC(C)CNC(=O)C(CCCOC1CCCCO1)CC(O)C(N)CC(C)C

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ANPEP P15144 1/20 0.33
DNPEP Q9ULA0 1/20 0.33
REN P00797 11/20 0.33
BACE1 P56817 2/20 0.32
MMP1 P03956 1/20 0.31
MMP8 P22894 1/20 0.31
CPB2 Q96IY4 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7427646 1.00 MEN1 (0.36) MEN1KMT2AANPEPDNPEPREN
SCHEMBL7294159 0.94 ANPEP (0.34) MEN1KMT2AANPEPDNPEPREN
SCHEMBL7294935 0.84 MEN1 (0.34) MEN1KMT2AANPEPDNPEPREN
SCHEMBL7285173 0.84 MEN1 (0.34) MEN1KMT2AANPEPDNPEPREN
SCHEMBL7295620 0.83 MMP1 (0.33) ANPEPDNPEPRENBACE1MMP1
SCHEMBL7288644 0.73 MEN1 (0.32) MEN1KMT2A
SCHEMBL7289080 0.71 MEN1 (0.39) MEN1KMT2ASMN1; SMN2
SCHEMBL11803199 0.70 MEN1 (0.44) MEN1KMT2A
SCHEMBL17662477 0.69 MEN1 (0.45) MEN1KMT2A
SCHEMBL10452842 0.69 CNR2 (0.58) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264106-A2 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-04-20 EP disclosed