SCHEMBL7288644

SCHEMBL7288644

CC(C)CNC(=O)C(=C[C@H](O)[C@@H](N)CC(C)C)CCOC1CCCCO1

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7286686 0.87 MEN1 (0.36) MEN1KMT2A
SCHEMBL7294159 0.74 ANPEP (0.34) MEN1KMT2A
SCHEMBL7278906 0.74 ANPEP (0.39) MEN1KMT2A
SCHEMBL7284497 0.74 ANPEP (0.39) MEN1KMT2A
SCHEMBL7427646 0.73 MEN1 (0.36) MEN1KMT2A
SCHEMBL7285244 0.73 MEN1 (0.36) MEN1KMT2A
SCHEMBL7317760 0.72 ANPEP (0.38)
SCHEMBL7287224 0.72 CTSK (0.36) MEN1KMT2A
SCHEMBL7320327 0.72 MEN1 (0.31) MEN1KMT2A
SCHEMBL7279294 0.71 ANPEP (0.41) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0272583-B1 5-SUBSTITUTED AMINO-4-HYDROXY-PENTENOIC ACID DERIVATIVES AND THEIR USE Banyu Pharmaceutical Co., Ltd. (JP) 1993-09-15 EP disclosed
US-4927565-A HYPOTENSIVE AGENT BANYU PHARMACEUTICAL CO., LTD. (JP) 1990-05-22 US disclosed