SCHEMBL7294159

SCHEMBL7294159

CC(C)CNC(=O)C(CCOC1CCCCO1)C[C@H](O)[C@@H](N)CC(C)C

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.34
DNPEP Q9ULA0 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
MMP1 P03956 1/20 0.32
MMP8 P22894 1/20 0.32
REN P00797 5/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
BACE1 P56817 5/20 0.31
CTSD P07339 3/20 0.31
EPHX1 P07099 1/20 0.30
PEPD P12955 2/20 0.30
METAP2 P50579 1/20 0.30
XPNPEP1 Q9NQW7 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7285244 0.94 MEN1 (0.36) ANPEPDNPEPMEN1KMT2AMMP1
SCHEMBL7427646 0.94 MEN1 (0.36) ANPEPDNPEPMEN1KMT2AMMP1
SCHEMBL7294935 0.90 MEN1 (0.34) ANPEPDNPEPMEN1KMT2AMMP1
SCHEMBL7285173 0.90 MEN1 (0.34) ANPEPDNPEPMEN1KMT2AMMP1
SCHEMBL7295620 0.85 MMP1 (0.33) ANPEPDNPEPMMP1MMP8REN
SCHEMBL7288644 0.74 MEN1 (0.32) MEN1KMT2A
SCHEMBL7267782 0.70 ANPEP (0.46) ANPEPDNPEPMMP1MMP8REN
SCHEMBL9417999 0.70 ANPEP (0.46) ANPEPDNPEPMMP1MMP8REN
SCHEMBL7267777 0.70 ANPEP (0.46) ANPEPDNPEPMMP1MMP8REN
Hydrochloric Acid SCHEMBL7274890 0.69 ANPEP (0.45) ANPEPDNPEPMMP1MMP8REN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0264106-B1 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use BANYU PHARMA CO LTD (JP) 1994-03-16 EP disclosed
US-4851387-A RENIN INHIBITORS BANYU PHARMACEUTICAL CO., LTD. (JP) 1989-07-25 US disclosed
EP-0264106-A2 5-Substituted amino-4-hydroxy-pentanoic acid derivatives and their use Banyu Pharmaceutical Co., Ltd. (JP) 1988-04-20 EP disclosed