Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285845 | 0.71 | MMP1 (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7293823 | 0.71 | — | — | |
| Water SCHEMBL10565308 | 0.70 | — | — | |
| SCHEMBL7286157 | 0.67 | GRIN2D (0.32) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7293169 | 0.59 | MMP1 (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL21477663 | 0.57 | CA12 (0.30) | — | |
| SCHEMBL16093372 | 0.56 | CA12 (0.38) | — | |
| SCHEMBL11316991 | 0.55 | — | — | |
| SCHEMBL23273584 | 0.55 | IDH1 (0.40) | ALDH1A1 | |
| SCHEMBL11992345 | 0.55 | MAPT (0.40) | NPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |