Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7286224 | 0.84 | — | — | |
| SCHEMBL7287110 | 0.71 | ALDH1A1 (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| SCHEMBL7286062 | 0.70 | MAPK14 (0.30) | — | |
| SCHEMBL7285845 | 0.68 | MMP1 (0.35) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7285501 | 0.67 | NPC1 (0.33) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL7286003 | 0.67 | PKM (0.40) | GRIN1GRIN2BALDH1A1SMN1; SMN2 | |
| SCHEMBL10463822 | 0.67 | ELANE (0.37) | GRIN2DGRIN3BGRIN1GRIN2AGRIN2B | |
| Hydrochloric Acid SCHEMBL7295298 | 0.66 | PKM (0.39) | GRIN1GRIN2BALDH1A1SMN1; SMN2 | |
| SCHEMBL7295809 | 0.66 | MAPK8 (0.37) | NPC1ALDH1A1RAB9ASMN1; SMN2 | |
| SCHEMBL10567467 | 0.66 | MAPK8 (0.37) | NPC1ALDH1A1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | claimed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |