Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7285845 | 0.85 | MMP1 (0.35) | MMP1MMP9MMP12GPR84ALDH1A1 | |
| SCHEMBL7295305 | 0.69 | GPR84 (0.38) | MMP1MMP9MMP12GPR84 | |
| SCHEMBL10562882 | 0.67 | GPR84 (0.33) | MMP1MMP9MMP12GPR84KMT2A | |
| SCHEMBL7292469 | 0.64 | MMP1 (0.34) | MMP1MMP9MMP12GPR84 | |
| SCHEMBL7295372 | 0.63 | GPR84 (0.36) | MMP1MMP9MMP12GPR84ABCB1 | |
| SCHEMBL7285267 | 0.61 | PKM (0.47) | MMP1MMP9MMP12ALDH1A1SMN1; SMN2 | |
| SCHEMBL7296669 | 0.61 | GPR84 (0.44) | MMP1MMP9MMP12GPR84ALDH1A1 | |
| Hydrochloric Acid SCHEMBL7296041 | 0.60 | PKM (0.46) | MMP1MMP9MMP12ALDH1A1KMT2A | |
| SCHEMBL7285501 | 0.59 | NPC1 (0.33) | ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11895717 | 0.58 | GPR84 (0.41) | MMP1MMP9MMP12GPR84ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | claimed |
| EP-0239533-B1 | PYRIDINE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-09-16 | — | — | EP | disclosed |
| US-4863938-A | Pyridine derivatives and their use as nootropic agents | CIBA-GEIGY CORPORATION (US) | 1989-09-05 | — | — | US | disclosed |