SCHEMBL728599

SCHEMBL728599

CCO[SiH](OCC)OCc1ccccc1S

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.30
SLC6A4 P31645 1/20 0.30
SLC6A3 Q01959 1/20 0.30
MAPT P10636 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3713272 0.81 L3MBTL1 (0.39) SLC6A2SLC6A4MAPTNPSR1L3MBTL1
SCHEMBL730291 0.79 FOLH1 (0.36)
SCHEMBL730413 0.77
SCHEMBL730414 0.77 NLRP3 (0.30)
SCHEMBL28070604 0.76 IDO1 (0.33) SLC6A2SLC6A4SLC6A3MAPTNPSR1
SCHEMBL729819 0.76 CYP4F2 (0.34)
Naphthalene SCHEMBL28826709 0.75 CYP2A6 (0.42) L3MBTL1
SCHEMBL838793 0.72 TSHR (0.46) SLC6A2SLC6A3MAPTL3MBTL1
SCHEMBL18297922 0.72 TSHR (0.46) SLC6A2SLC6A3MAPTL3MBTL1
SCHEMBL8216348 0.71 IDO1 (0.38) MAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
EP-2393861-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY Momentive Performance Materials Inc. (US) 2011-12-14 EP claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
WO-2010091338-A1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-08-12 WO claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed