SCHEMBL730291

SCHEMBL730291

CCO[SiH](OCC)OCc1ccccc1CCS

nearest known ligand 0.36

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 6/20 0.36
CYP4F2 P78329 1/20 0.32
CYP4A11 Q02928 1/20 0.32
ADRA2A P08913 1/20 0.31
ADRA2B P18089 1/20 0.31
ADRA2C P18825 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL729819 0.90 CYP4F2 (0.34) CYP4F2CYP4A11ADRA2AADRA2BADRA2C
SCHEMBL3713272 0.82 L3MBTL1 (0.39) CYP4F2CYP4A11
SCHEMBL728599 0.79 SLC6A2 (0.30)
SCHEMBL29362123 0.72 FOLH1 (0.56) FOLH1
SCHEMBL330664 0.72 FOLH1 (0.56) FOLH1
SCHEMBL730414 0.71 NLRP3 (0.30)
SCHEMBL14651449 0.71 FOLH1 (0.52) FOLH1CYP4F2CYP4A11
SCHEMBL838793 0.70 TSHR (0.46)
SCHEMBL18297922 0.70 TSHR (0.46)
Naphthalene SCHEMBL28826709 0.68 CYP2A6 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP claimed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US claimed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US claimed
EP-2393861-B1 MOISTURE-CURABLE SILYLATED POLYMER POSSESSING IMPROVED STORAGE STABILITY MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-23 EP disclosed
US-8138297-B2 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-20 US disclosed
US-20100204384-A1 Moisture-curable silylated polymer possessing improved storage stability MOMENTIVE PERFORMANCE MATERIALS INC. 2010-08-12 US disclosed