Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.45 |
| ▸ | TACR2 | P21452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8843289 | 0.89 | POLB (0.54) | POLBUSP2HTTALDH1A1LMNA | |
| SCHEMBL8843510 | 0.85 | HTR1A (0.40) | POLBKMT2A | |
| SCHEMBL7287015 | 0.80 | TACR2 (0.54) | POLBALDH1A1LMNAKMT2AHPGD | |
| SCHEMBL30882632 | 0.78 | MASP2 (0.59) | ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL15669228 | 0.75 | TLR2 (0.43) | ALDH1A1 | |
| SCHEMBL15669229 | 0.75 | TLR2 (0.43) | ALDH1A1 | |
| SCHEMBL8337943 | 0.75 | HTT (0.52) | POLBUSP2HTTALDH1A1LMNA | |
| SCHEMBL22322972 | 0.75 | ALDH1A1 (0.54) | HTTALDH1A1LMNACYP2C19MAPT | |
| SCHEMBL8843457 | 0.75 | GAA (0.41) | ALDH1A1LMNAMAPTHPGD | |
| SCHEMBL6428465 | 0.75 | ALDH1A1 (0.55) | POLBALDH1A1LMNAKMT2ATACR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5948780-A | ADMINISTERING A METALLOPROTEINASE INHIBITOR | WARNER-LAMBERT COMPANY (US) | 1999-09-07 | — | — | US | disclosed |
| US-5672615-A | MATRIX-DEGRADING METALLOPROTEINASE INHIBITORS | NOVARTIS CORPORATION (US) | 1997-09-30 | — | — | US | disclosed |