Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | SLC8B1 | Q6J4K2 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.39 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.39 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.39 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.39 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.39 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7287458 | 0.81 | ALDH1A1 (0.42) | MAPTTSHRTP53ALOX15RECQL | |
| SCHEMBL7286888 | 0.73 | ALDH1A1 (0.43) | MAPTTSHRALDH1A1LMNAHTT | |
| SCHEMBL8155584 | 0.71 | IDO1 (0.62) | TP53CYP2C19LMNAIDO1 | |
| SCHEMBL4800295 | 0.68 | ALDH1A1 (0.49) | MAPTTSHRTP53CYP1A2ALOX15 | |
| SCHEMBL4495147 | 0.68 | ALDH1A1 (0.49) | MAPTTSHRTP53CYP1A2ALOX15 | |
| SCHEMBL8802497 | 0.68 | HSD17B10 (0.49) | MAPTTSHRTP53CYP1A2ALOX15 | |
| SCHEMBL8905187 | 0.68 | ALDH1A1 (0.49) | MAPTTSHRTP53CYP1A2ALOX15 | |
| SCHEMBL8853352 | 0.68 | ALDH1A1 (0.66) | MAPTTSHRCYP1A2ALOX15RECQL | |
| SCHEMBL3149958 | 0.68 | AHR (0.39) | MAPTTSHRTP53CYP1A2CYP2C9 | |
| SCHEMBL7287889 | 0.68 | MAPT (0.47) | MAPTTSHRTP53ALOX15RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5063225-A | Antiarrhythmia | ROUSSEL UCLAF (FR) | 1991-11-05 | — | — | US | disclosed |