Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.47 |
| ▸ | PREP | P48147 | 6/20 | 0.46 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.44 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7294053 | 0.91 | FKBP1A (0.50) | DPP4FKBP1A | |
| SCHEMBL7286213 | 0.87 | PREP (0.55) | PREP | |
| SCHEMBL7286320 | 0.87 | PREP (0.55) | PREP | |
| SCHEMBL9662089 | 0.82 | ALDH1A1 (0.60) | FKBP1APREP | |
| SCHEMBL7359197 | 0.81 | FKBP1A (0.47) | DPP4FKBP1APREPGRIN2BP2RX4 | |
| SCHEMBL9545141 | 0.77 | DPP4 (0.54) | DPP4PREPDPP8DPP9DPP7 | |
| SCHEMBL6375414 | 0.76 | KMT2A (0.41) | PREP | |
| SCHEMBL5702212 | 0.76 | SMN1; SMN2 (0.49) | FKBP1APREPGRIN2BP2RX4 | |
| SCHEMBL7875376 | 0.76 | SMN1; SMN2 (0.49) | FKBP1APREPGRIN2BP2RX4 | |
| SCHEMBL5702226 | 0.76 | SMN1; SMN2 (0.49) | FKBP1APREPGRIN2BP2RX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| EP-0602209-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-06-22 | — | — | EP | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| WO-1994001113-A1 | OXYTOCIN ANTAGONIST | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1994-01-20 | — | — | WO | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |