Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | FABP5 | Q01469 | 3/20 | 0.41 |
| ▸ | FABP7 | O15540 | 2/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 3/20 | 0.38 |
| ▸ | PREP | P48147 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001858 | 0.89 | PREP (0.50) | PREP | |
| SCHEMBL6161418 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL12644111 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL6161890 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL21961543 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL23157205 | 0.82 | KMT2A (0.43) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL118354 | 0.81 | ALDH1A1 (0.58) | KMT2AFABP5FABP7F2PREP | |
| SCHEMBL1002927 | 0.81 | ALDH1A1 (0.58) | KMT2AFABP5FABP7F2PREP | |
| SCHEMBL14891093 | 0.81 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2F2 | |
| SCHEMBL2043044 | 0.81 | L3MBTL1 (0.45) | KMT2AFABP5FABP7EPHX2F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1001764-A4 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO INC (US) | 2005-08-24 | — | — | EP | disclosed |
| US-6903075-B1 | Heterocyclic amide compounds as cell adhesion inhibitors | MERCK & CO., INC. (US) | 2005-06-07 | — | — | US | disclosed |
| EP-1001764-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | Merck & Co., Inc. (a New Jersey corp.) (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999064395-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1999-12-16 | — | — | WO | disclosed |
| WO-1998053814-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS CELL ADHESION INHIBITORS | MERCK & CO., INC. (US) | 1998-12-03 | — | — | WO | disclosed |
| EP-0502926-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INT (US) | 1992-09-16 | — | — | EP | disclosed |
| EP-0502926-A4 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES. | RHONE POULENC RORER INTERNAT H (US) | 1992-07-13 | — | — | EP | disclosed |
| WO-1991007976-A1 | ANTI-THROMBOTIC PEPTIDES AND PSEUDOPEPTIDES | RHONE-POULENC RORER INTERNATIONAL (HOLDINGS) INC. (US) | 1991-06-13 | — | — | WO | disclosed |