Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.53 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.52 |
| ▸ | LTA4H | P09960 | 2/20 | 0.51 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.50 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.50 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | LAP3 | P28838 | 1/20 | 0.50 |
| ▸ | ELANE | P08246 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL313062 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| SCHEMBL2135198 | 1.00 | ALDH1A1 (0.60) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL629929 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL2135194 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL1764407 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL16991480 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Benzene SCHEMBL28241584 | 0.98 | ALDH1A1 (0.58) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL21612229 | 0.96 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Alanine SCHEMBL28245512 | 0.96 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 | |
| Alanine SCHEMBL28245513 | 0.96 | ALDH1A1 (0.56) | ALDH1A1KMT2ATDP1MAPK1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 383 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3351551-B1 | PREPARATION METHOD OF NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS AND INTERMEDIATES THEREOF | BRIGHTGENE BIO MEDICAL TECH CO LTD (CN) | 2022-12-07 | — | — | EP | claimed |
| CN-113354931-A | Preparation method of PLA modified material | 晋江凯基高分子材料有限公司 | 2021-09-07 | — | — | CN | claimed |
| CN-112409652-A | Formula and production process of environment-friendly recycled transparent rubber and plastic material | 晋江森溢新材料科技有限公司 | 2021-02-26 | — | — | CN | claimed |
| CN-112250924-A | Formula and production process of environment-friendly recycled high-wear-resistance rubber and plastic material | 晋江森溢新材料科技有限公司 | 2021-01-22 | — | — | CN | claimed |
| US-20180237466-A1 | Preparation Method of Nucleoside Phosphoramidate Prodrugs and Intermediates Thereof | BRIGHTGENE BIO-MEDICAL TECHNOLOGY CO., LTD. (CN) | 2018-08-23 | — | — | US | claimed |
| EP-3351551-A1 | PREPARATION METHOD OF NUCLEOSIDE PHOSPHORAMIDATE PRODRUGS AND INTERMEDIATES THEREOF | BrightGene Bio-Medical Technology Co., Ltd. (CN) | 2018-07-25 | — | — | EP | claimed |
| CN-108026271-A | The macromolecule conjugate of 6 coordinate platinum complex | 日本化药株式会社 | 2018-05-11 | — | — | CN | claimed |
| CN-106749438-A | A kind of Amadori compound synthesis method | 华宝香精股份有限公司 | 2017-05-31 | — | — | CN | claimed |
| CN-103159827-B | (1R, 3S)-1-p-nitrophenyl-tetrahydro-beta-carboline amic acid, its synthesis, anti-thrombus activity and application | Capital Medical University (CN) | 2016-03-30 | — | — | CN | claimed |
| CN-103159758-B | (1S, 3S)-1-p-nitrophenyl-1,2,3,4-tetrahydro-beta-carboline amic acid, its synthesis, anti-thrombus activity and the application as antithrombotic agent | Capital Medical University (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-1931854-A | Intermediate for synthesizing fasidotril and its synthesis use | SHANGHAI INST OF MEDICINE INDU (CN) | 2007-03-21 | — | — | CN | claimed |
| US-6677483-B2 | DISSOLVING DIETHYLENETRIAMINEPENTAACETIC- BISANHYDRIDE OF FORMULA IN DIMETHYL SULFOXIDE OR IN DIMETHYLFORMAMIDE OR IN A MIXTURE; ADDING SOLUBILIZER, AN AUXILIARY BASE AND A MONOAMINE OR DIAMINE, HEATING | SCHERING AG (DE) | 2004-01-13 | — | — | US | claimed |
| US-20020155065-A1 | Process for the production of monoamides of DTPA | SCHERING AG (DE) | 2002-10-24 | — | — | US | claimed |
| CN-1178788-A | Angiotensin invertase inhibitor contaiing 2 ,4 -methylene proline and its sythesis and use | SHANGHAI INST ORGANIC CHEM (CN) | 1998-04-15 | — | — | CN | claimed |
| US-5602161-A | ELASTASE INHIBITORS; PREVENTING AND TREATING EMPHYSEMA, ENDOTOXIN-INDUCED LUNG DISORDERS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1997-02-11 | — | — | US | claimed |
| EP-0676396-A1 | Tetrazolylphenyl pivalate derivatives and medicinal composition containing the same as effective component | Wakamoto Pharmaceutical Co., Ltd. (JP) | 1995-10-11 | — | — | EP | claimed |
| CN-1106386-A | Synthetic process of Ramipril | UNIV BEIJING (CN) | 1995-08-09 | — | — | CN | claimed |
| CN-1003124-B | Method for synthesizing ben butyl propylprolic acid | 国家医药管理局上海医药工业研究院 | 1989-01-25 | — | — | CN | claimed |
| CN-85105258-A | Process for synthesising enalapril | — | 1986-12-31 | — | — | CN | claimed |
| US-4558034-A | Inhibitors of bacterial collagenase | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF KENTUCKY (US) | 1985-12-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020155065-A1 | Process for the production of monoamides of DTPA | NAAA, PAM, DNPEP | ALDH1A1 4498/4885KMT2A 248/4885TDP1 3902/4885 |
| US-20180237466-A1 | Preparation Method of Nucleoside Phosphoramidate Prodrugs and Intermediates Thereof | PNP, PAPSS1, TYMP | ALDH1A1 911/4885KMT2A 3921/4885TDP1 159/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.