SCHEMBL7287683

SCHEMBL7287683

[CH]=CCCC/C=C/CCCC

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.43
FAAH O00519 4/20 0.42
F7 P08709 2/20 0.41
F3 P13726 2/20 0.41
TSHR P16473 2/20 0.39
ALDH1A1 P00352 1/20 0.39
TERT O14746 3/20 0.37
CYP1A2 P05177 2/20 0.37
MAPT P10636 2/20 0.37
CYP2C19 P33261 2/20 0.37
BLM P54132 2/20 0.37
HSD17B10 Q99714 2/20 0.37
FABP4 P15090 2/20 0.37
PTPN1 P18031 2/20 0.37
PPARG P37231 2/20 0.37
KMT2A Q03164 2/20 0.37
PPARD Q03181 2/20 0.37
PPARA Q07869 2/20 0.37
GMNN O75496 1/20 0.37
USP2 O75604 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7287688 1.00 TRPV1 (0.43) TRPV1FAAHF7F3TSHR
SCHEMBL29284395 0.97 TRPV1 (0.41) TRPV1FAAHF7F3TSHR
SCHEMBL28731047 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL21694647 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL29284513 0.92 TRPV1 (0.41) TRPV1FAAHF7F3TSHR
SCHEMBL25182584 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL25185977 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL25178870 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL21694646 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT
SCHEMBL28996051 0.92 FAAH (0.52) TRPV1FAAHF7F3TERT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12031130-B2 Composition for modifying target gene TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-07-09 US disclosed
US-11993570-B2 Cationic lipids TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2024-05-28 US disclosed
EP-3733641-B1 CATIONIC LIPIDS TAKEDA PHARMACEUTICALS CO (JP) 2024-04-10 EP disclosed
CN-111511713-B Cationic lipid 武田药品工业株式会社 2024-01-02 CN disclosed
CN-111527204-B Composition for target gene modification 国立大学法人京都大学 2023-09-01 CN disclosed
US-20230257338-A1 CATIONIC LIPIDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-08-17 US disclosed
US-20210371854-A1 COMPOSITION FOR MODIFYING TARGET GENE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-12-02 US disclosed
EP-3733844-A1 COMPOSITION FOR MODIFYING TARGET GENE Kyoto University (JP) 2020-11-04 EP disclosed
EP-3733641-A1 CATIONIC LIPIDS Takeda Pharmaceutical Company Limited (JP) 2020-11-04 EP disclosed
US-20200331841-A1 CATIONIC LIPIDS TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2020-10-22 US disclosed
US-5786367-A OXYGEN SCAVENGERS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1998-07-28 US disclosed
EP-0719258-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-07-03 EP disclosed
WO-1996002508-A1 CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1996-02-01 WO disclosed
US-5306719-A Cardiotonic agents OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-04-26 US disclosed
EP-0255134-B1 CARBOSTYRIL DERIVATIVES AND SALTS THEREOF, PROCESS FOR PREPARING THEM, AND CARDIOTONIC COMPOSITION CONTAINING SAME OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-03-03 EP disclosed
US-5071856-A CARBOSTYRIL DERIVATIVES AND SALTS THEREOF OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-12-10 US disclosed
US-4886809-A CARDIOTONIC AGENTS OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-12-12 US disclosed
US-4845100-A WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1989-07-04 US disclosed
EP-0255134-A2 Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-02-03 EP disclosed
EP-0202760-A2 Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1986-11-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11993570-B2 Cationic lipids ELOVL5, LPCAT3, ELOVL3 TRPV1 1432/4885FAAH 1807/4885F7 453/4885
US-20210371854-A1 COMPOSITION FOR MODIFYING TARGET GENE NSUN2, NSUN3, RNASE1 TRPV1 4572/4885FAAH 3436/4885F7 1095/4885
US-12031130-B2 Composition for modifying target gene NSUN2, NSUN3, RNASE1 TRPV1 4572/4885FAAH 3436/4885F7 1095/4885
US-20230257338-A1 CATIONIC LIPIDS ELOVL5, LPCAT3, ELOVL3 TRPV1 1432/4885FAAH 1807/4885F7 453/4885
US-20200331841-A1 CATIONIC LIPIDS ELOVL5, LPCAT3, ELOVL3 TRPV1 1432/4885FAAH 1807/4885F7 453/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.