Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28762240 | 0.72 | SIGMAR1 (0.37) | LMNAMEN1KMT2AALDH1A1POLB | |
| SCHEMBL27651189 | 0.71 | MC4R (0.44) | SMN1; SMN2TSHRLMNAPOLB | |
| SCHEMBL28562009 | 0.68 | SIGMAR1 (0.39) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| Sulfuric Acid SCHEMBL28566708 | 0.68 | MAPK1 (0.43) | SMN1; SMN2TSHRLMNANOTUMALDH1A1 | |
| Hydrochloric Acid SCHEMBL28555650 | 0.67 | SIGMAR1 (0.38) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL7287729 | 0.66 | KEAP1 (0.41) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL28567336 | 0.65 | SIGMAR1 (0.36) | SMN1; SMN2TSHRLMNAMEN1KMT2A | |
| SCHEMBL17785185 | 0.63 | LMNA (0.43) | SMN1; SMN2TSHRLMNANOTUMCYP2D6 | |
| Hydrochloric Acid SCHEMBL3156656 | 0.62 | ABL1 (0.56) | TSHRMEN1KMT2A | |
| Thiocyanic Acid SCHEMBL28564599 | 0.62 | MEN1 (0.34) | SMN1; SMN2TSHRLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0307837-A2 | Renin-inhibiting peptidyl heterocycles | ABBOTT LABORATORIES (US) | 1989-03-22 | — | — | EP | disclosed |