Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11130899 | 1.00 | TSHR (0.41) | TSHRRNPEPCA12CA9LMNA | |
| Acetic Acid SCHEMBL11102119 | 0.94 | RNPEP (0.41) | TSHRRNPEPCA12CA9LMNA | |
| SCHEMBL12038890 | 0.85 | RNPEP (0.42) | TSHRRNPEPLMNAMEN1KMT2A | |
| SCHEMBL12597432 | 0.85 | RNPEP (0.42) | TSHRRNPEPLMNAMEN1KMT2A | |
| SCHEMBL18647533 | 0.85 | RNPEP (0.42) | TSHRRNPEPLMNAMEN1KMT2A | |
| SCHEMBL28558305 | 0.83 | TSHR (0.41) | TSHRRNPEPCA12CA9LMNA | |
| SCHEMBL538340 | 0.82 | TSHR (0.54) | TSHRRNPEPCA12CA9LMNA | |
| SCHEMBL538339 | 0.82 | TSHR (0.54) | TSHRRNPEPCA12CA9LMNA | |
| SCHEMBL17928531 | 0.81 | TSHR (0.43) | TSHRRNPEPLMNAMEN1KMT2A | |
| SCHEMBL7767616 | 0.81 | LMNA (0.44) | TSHRCA12CA9LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0050503-B1 | PHARMACOLOGICALLY ACTIVE PENTAPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | claimed |
| EP-0050503-A1 | Pharmacologically active pentapeptide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | claimed |
| US-5252560-A | Cyclic imide derivatives, compositions and use | GLAXO INC. (US) | 1993-10-12 | — | — | US | disclosed |
| EP-0520573-A1 | Cyclic imide derivatives | GLAXO INC. (US) | 1992-12-30 | — | — | EP | disclosed |
| EP-0050503-B1 | PHARMACOLOGICALLY ACTIVE PENTAPEPTIDE DERIVATIVES | ELI LILLY AND COMPANY (US) | 1984-07-04 | — | — | EP | disclosed |
| EP-0050503-A1 | Pharmacologically active pentapeptide derivatives | ELI LILLY AND COMPANY (US) | 1982-04-28 | — | — | EP | disclosed |
| EP-0030848-A2 | Pharmacologically active peptides, their preparation and pharmaceutical compositions containing them | ELI LILLY AND COMPANY (US) | 1981-06-24 | — | — | EP | disclosed |