SCHEMBL538339

SCHEMBL538339

CSCCC(NC(N)=O)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.41
RNPEP Q9H4A4 1/20 0.39
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538340 1.00 TSHR (0.54) TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL538037 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL3282392 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL538038 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL11032203 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL1694616 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL1694618 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL14480446 0.86 TSHR (0.47) TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL7765985 0.83 LMNA (0.44) TSHRSMN1; SMN2CA12CA9LMNA
SCHEMBL7767616 0.83 LMNA (0.44) TSHRSMN1; SMN2CA12CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117377654-A Method for producing methionine 安迪苏法国联合股份有限公司 2024-01-09 CN claimed
EP-2750775-B1 METHOD FOR PRODUCING A METHIONINE SALT EVONIK OPERATIONS GMBH (DE) 2020-12-09 EP disclosed
CN-105061555-B The preparation and use of the methionyl methionine of feed addictive as fish and shellfish 赢创德固赛有限公司 2019-07-30 CN disclosed
CN-105053577-B The preparation and use of the methionyl methionine of feed addictive as fish and shellfish 赢创德固赛有限公司 2019-05-07 CN disclosed
US-9403764-B2 Method of production of a methionine salt EVONIK DEGUSSA GMBH (DE) 2016-08-02 US disclosed
US-9403764-B2 Method of production of a methionine salt EVONIK DEGUSSA GMBH (DE) 2016-08-02 US disclosed
CN-105061555-A Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2015-11-18 CN disclosed
CN-105053577-A Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2015-11-18 CN disclosed
US-20150223495-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2015-08-13 US disclosed
US-9095161-B2 Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH (DE) 2015-08-04 US disclosed
EP-2348881-A1 PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS Evonik Degussa GmbH (DE) 2011-08-03 EP disclosed
WO-2010112365-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2010-10-07 WO disclosed
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2010-09-30 US disclosed
CN-101720858-A Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2010-06-09 CN disclosed
US-20100098801-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2010-04-22 US disclosed
WO-2010043558-A1 PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2010-04-22 WO disclosed
US-20050176115-A1 Process for the production of methionine NIPPON SODA CO., LTD. (JP) 2005-08-11 US disclosed
EP-1541691-A1 PROCESS FOR THE PRODUCTION OF METHIONINE NIPPON SODA CO., LTD. (JP) 2005-06-15 EP disclosed
US-6333176-B1 ENZYMATIC CLEAVAGE OF C-TERMINAL AMINO GROUP FROM PEPTIDE AMIDE, DEAMINATION WITH PEPTIDE AMIDASE, INCUBATION AND INOCULATION DEGUSSA AKTIENGESELLSCHAFT (DE) 2001-12-25 US disclosed
EP-0759066-B1 PROCESS FOR OBTAINING MICRO-ORGANISMS CONTAINING PEPTIDE AMIDASE, MICRO-ORGANISMS OBTAINED THEREWITH, PEPTIDE AMIDASES CONTAINED IN THEM AND USE THEREOF DEGUSSA (DE) 2001-06-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES AADAT, BCAT2, SLC7A11 TSHR 906/4885MEN1 1811/4885KMT2A 533/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.