SCHEMBL538340

SCHEMBL538340

CSCC[C@H](NC(N)=O)C(N)=O

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.46
CA12 O43570 1/20 0.45
CA9 Q16790 1/20 0.45
MAPT P10636 1/20 0.41
LMNA P02545 1/20 0.41
RNPEP Q9H4A4 1/20 0.39
CA2 P00918 2/20 0.39
CA1 P00915 1/20 0.39
ALDH1A1 P00352 2/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL538339 1.00 TSHR (0.54) TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL538037 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL3282392 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL538038 0.86 LMNA (0.54) TSHRLMNARNPEPCA2CA1
SCHEMBL11032203 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL1694616 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL1694618 0.86 CA12 (0.44) TSHRSMN1; SMN2CA12CA9MAPT
SCHEMBL14480446 0.86 TSHR (0.47) TSHRMEN1KMT2ASMN1; SMN2CA12
SCHEMBL7765985 0.83 LMNA (0.44) TSHRSMN1; SMN2CA12CA9LMNA
SCHEMBL7767616 0.83 LMNA (0.44) TSHRSMN1; SMN2CA12CA9LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4299581-A1 METHOD FOR THE PREPARATION OF DL-METHIONINE AND DIASTEREOMERICALLY PURE PREPARATIO OF DLLD METHIONYLMETHIONINE Evonik Operations GmbH (DE) 2024-01-03 EP disclosed
WO-2023067061-A1 PRECURSORS FOR THE PREPARATION OF DL-METHIONINE AND DLLD-METHIONYLMETHIONINE EVONIK OPERATIONS GMBH (DE) 2023-04-27 WO disclosed
WO-2023067059-A1 PROCESS FOR PRODUCING DL-METHIONINE AND DLLD-METHIONYLMETHIONINE EVONIK OPERATIONS GMBH (DE) 2023-04-27 WO disclosed
CN-105053577-B The preparation and use of the methionyl methionine of feed addictive as fish and shellfish 赢创德固赛有限公司 2019-05-07 CN disclosed
US-20180194804-A1 SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE EVONIK DEGUSSA GMBH (DE) 2018-07-12 US disclosed
EP-3319946-A1 SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)-1,4-DIKETOPIPERAZINE Evonik Degussa GmbH (DE) 2018-05-16 EP disclosed
WO-2017005547-A1 SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)-1,4-DIKETOPIPERAZINE EVONIK DEGUSSA GMBH (DE) 2017-01-12 WO disclosed
CN-105053577-A Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2015-11-18 CN disclosed
CN-105061555-A Preparation and use of methionylmethionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2015-11-18 CN disclosed
US-20150223495-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2015-08-13 US disclosed
US-20140205711-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2014-07-24 US disclosed
EP-2348881-B1 PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2013-09-04 EP disclosed
US-20130008384-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2013-01-10 US disclosed
EP-2413711-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE Evonik Degussa GmbH (DE) 2012-02-08 EP disclosed
CN-102186358-A Preparation and use of methionyl methionine as feed additive for fish and crustaceans EVONIK DEGUSSA GMBH 2011-09-14 CN disclosed
EP-2348881-A1 PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS Evonik Degussa GmbH (DE) 2011-08-03 EP disclosed
WO-2010112365-A1 DIPEPTIDE AS FEEDSTUFF ADDITIVE EVONIK DEGUSSA GMBH (DE) 2010-10-07 WO disclosed
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES EVONIK DEGUSSA GMBH (DE) 2010-09-30 US disclosed
US-20100098801-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2010-04-22 US disclosed
WO-2010043558-A1 PRODUCTION AND USE OF METHIONYL-METHIONINE AS A FEED ADDITIVE FOR FISH AND CRUSTACEANS EVONIK DEGUSSA GMBH (DE) 2010-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100247707-A1 DIPEPTIDES AS FEED ADDITIVES AADAT, BCAT2, SLC7A11 TSHR 906/4885MEN1 1811/4885KMT2A 533/4885
US-20130008384-A1 PREPARATION AND USE OF METHIONYLMETHIONINE AS FEED ADDITIVE FOR FISH AND CRUSTACEANS MAT2B, MGMT, MTR TSHR 3186/4885MEN1 589/4885KMT2A 704/4885
US-20180194804-A1 SIMPLIFIED AND SCALABLE METHOD FOR SYNTHESIS OF 2,6-BIS(METHIONYL)- 1,4-DIKETOPIPERAZINE METAP2, MTX2, METTL3 TSHR 1583/4885MEN1 219/4885KMT2A 315/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.