Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
| ▸ | BRS3 | P32247 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NPFFR1 | Q9GZQ6 | 8/20 | 0.55 |
| ▸ | NPFFR2 | Q9Y5X5 | 8/20 | 0.55 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7275612 | 0.86 | TACR1 (0.58) | ALDH1A1MEN1KMT2AKDM4EHRH4 | |
| SCHEMBL7272341 | 0.85 | SMN1; SMN2 (0.55) | ALDH1A1MEN1KMT2AKDM4ENPFFR1 | |
| SCHEMBL3659514 | 0.80 | HRH4 (0.64) | MEN1KMT2AHRH4 | |
| SCHEMBL8671111 | 0.80 | HRH4 (0.64) | MEN1KMT2AHRH4 | |
| SCHEMBL7295260 | 0.79 | DRD3 (0.60) | ALDH1A1MEN1KMT2AKDM4EOPRM1 | |
| SCHEMBL3662085 | 0.78 | HRH4 (0.60) | MEN1KMT2AHRH4 | |
| SCHEMBL3662089 | 0.78 | HRH4 (0.60) | MEN1KMT2AHRH4 | |
| SCHEMBL8671488 | 0.78 | HRH4 (0.60) | MEN1KMT2AHRH4OPRD1 | |
| SCHEMBL29078430 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ASIGMAR1KDM4E | |
| SCHEMBL30585259 | 0.77 | ALDH1A1 (0.73) | ALDH1A1MEN1KMT2ASIGMAR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5378690-A | Treatment of angiotensin induced hypertension | SANKYO COMPANY, LIMITED (JP) | 1995-01-03 | — | — | US | disclosed |
| EP-0274259-A2 | New renin-inhibitory oligopeptides, their preparaton and their use | Sankyo Company Limited (JP) | 1988-07-13 | — | — | EP | disclosed |