Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291296 | 0.89 | CACNA1S (0.42) | KCNH2POLBKMT2AKDM4EALDH1A1 | |
| SCHEMBL7289142 | 0.84 | DRD2 (0.42) | KMT2AKDM4EALDH1A1 | |
| SCHEMBL7288930 | 0.82 | RAB9A (0.39) | POLBMAPT | |
| SCHEMBL10996184 | 0.81 | CYP3A4 (0.47) | KCNH2POLBKMT2AHRH3MAOB | |
| SCHEMBL7281761 | 0.81 | ABCB1 (0.42) | — | |
| Oxalic Acid SCHEMBL10961999 | 0.81 | CYP3A4 (0.45) | KCNH2POLBKMT2AHRH3KDM4E | |
| SCHEMBL10996823 | 0.79 | CYP3A4 (0.45) | KCNH2KMT2AHRH3MAPT | |
| SCHEMBL10997041 | 0.79 | CYP3A4 (0.45) | KDM4EALDH1A1 | |
| SCHEMBL9748247 | 0.79 | RAB9A (0.40) | POLBMAPT | |
| SCHEMBL10995981 | 0.79 | CYP3A4 (0.44) | KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4584300-A | Platelet anti-aggregative- and calcium antagonistic -1,4-benzothiazin-3-one derivatives, compositions, and methods of use therefor | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1986-04-22 | — | — | US | claimed |
| EP-0116368-A1 | Benzothiazine derivatives | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-08-22 | — | — | EP | claimed |