Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288930 | 0.97 | RAB9A (0.39) | RAB9ACYP3A4LMNACACNA1SPOLB | |
| SCHEMBL9749448 | 0.88 | RAB9A (0.39) | RAB9ACYP3A4LMNACACNA1SPOLB | |
| SCHEMBL7298983 | 0.87 | HDAC3 (0.41) | CYP3A4LMNACACNA1SPOLB | |
| SCHEMBL9830525 | 0.86 | RAB9A (0.49) | RAB9ALMNACACNA1SPOLBMAPT | |
| SCHEMBL10674571 | 0.85 | LMNA (0.37) | CYP3A4LMNACACNA1SPOLBMAPT | |
| SCHEMBL10680075 | 0.85 | LMNA (0.36) | CYP3A4LMNACACNA1SMAPT | |
| SCHEMBL10675678 | 0.85 | LMNA (0.36) | CYP3A4LMNACACNA1SPOLBMAPT | |
| SCHEMBL7278811 | 0.84 | PTPN1 (0.41) | RAB9ACYP3A4LMNACACNA1SPOLB | |
| SCHEMBL10675827 | 0.84 | LMNA (0.36) | LMNACACNA1SMAPT | |
| Hydrochloric Acid SCHEMBL9748576 | 0.83 | ADRA1D (0.40) | RAB9ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0237573-B1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1992-01-15 | — | — | EP | disclosed |
| US-4786635-A | THERAPEUTIC AGENTS FOR CIRCULATORY DISEASES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1988-11-22 | — | — | US | disclosed |
| EP-0237573-A1 | NOVEL BENZOTHIAZINE DERIVATIVES | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1987-09-23 | — | — | EP | disclosed |