Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.69 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.56 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.56 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.56 |
| ▸ | NOS3 | P29474 | 1/20 | 0.55 |
| ▸ | NOS1 | P29475 | 1/20 | 0.55 |
| ▸ | NOS2 | P35228 | 1/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17875071 | 0.86 | EPHX1 (0.78) | EPHX1ACHEMEN1KMT2AL3MBTL3 | |
| SCHEMBL3111634 | 0.86 | RHOC (0.62) | EPHX1MEN1KMT2AEPHX2HPGD | |
| SCHEMBL7297189 | 0.86 | EPHX1 (0.57) | EPHX1KMT2AEPHX2USP2 | |
| SCHEMBL7297976 | 0.86 | EPHX1 (0.59) | EPHX1ACHEMEN1KMT2AL3MBTL3 | |
| SCHEMBL641306 | 0.85 | CCNC (0.57) | EPHX1ACHEMEN1KMT2APTPN2 | |
| SCHEMBL3801054 | 0.85 | SPR (0.50) | EPHX1EPHX2ALDH1A1 | |
| SCHEMBL5145670 | 0.82 | EPHX1 (1.00) | EPHX1ACHEMEN1KMT2AL3MBTL3 | |
| SCHEMBL4369698 | 0.82 | EPHX1 (0.82) | EPHX1ACHEMEN1KMT2AL3MBTL3 | |
| SCHEMBL10293612 | 0.82 | EPHX1 (0.71) | EPHX1ACHEMEN1KMT2AL3MBTL3 | |
| SCHEMBL7465143 | 0.82 | KDM4E (0.51) | EPHX1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5652247-A | VASOPRESSIN ANTAGONIST | OTSUKA PHARMACEUTICAL CO., LTD (JP) | 1997-07-29 | — | — | US | disclosed |
| US-5436254-A | Vaopressin antagonists | OTSUKA PHARMACEUTICAL COMPANY, LTD. (JP) | 1995-07-25 | — | — | US | disclosed |
| US-5356904-A | Administering to prevent preterm labor in mammals | MERCK & CO., INC. (US) | 1994-10-18 | — | — | US | disclosed |
| EP-0382185-B1 | Carbostyril derivatives | OTSUKA PHARMA CO LTD (JP) | 1994-06-15 | — | — | EP | disclosed |
| US-5225402-A | Vasopressin antagonist, vasodilation, hypotensive, diuretics and anticoagulants | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-06 | — | — | US | disclosed |
| EP-0382185-A2 | Carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1990-08-16 | — | — | EP | disclosed |