Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CPT2 | P23786 | 6/20 | 0.48 |
| ▸ | CPT1A | P50416 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MVD | P53602 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3187180 | 0.91 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL3187156 | 0.91 | ALDH1A1 (0.61) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL7299218 | 0.91 | KMT2A (0.51) | ALDH1A1KMT2ACPT2CPT1ASMN1; SMN2 | |
| SCHEMBL7290619 | 0.88 | KMT2A (0.53) | ALDH1A1KMT2ACPT2CPT1ASMN1; SMN2 | |
| SCHEMBL7297177 | 0.86 | KMT2A (0.56) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL5743864 | 0.85 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL3148212 | 0.85 | ALDH1A1 (0.63) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL5741156 | 0.85 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL5741958 | 0.85 | KMT2A (0.65) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A | |
| SCHEMBL5743409 | 0.85 | L3MBTL1 (0.60) | ALDH1A1L3MBTL1KMT2ACPT2CPT1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915088-B1 | D-Proline derivatives | HOFFMANN LA ROCHE (CH) | 2002-09-18 | — | — | EP | claimed |