SCHEMBL7299218 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	KMT2A	Q03164	6/20	0.51

▸	MEN1	O00255	5/20	0.51

▸	ALDH1A1	P00352	1/20	0.49

▸	SMN1; SMN2	Q16637	1/20	0.49

▸	CPT2	P23786	10/20	0.48

▸	CPT1A	P50416	10/20	0.48

▸	POLB	P06746	1/20	0.46

▸	PSMD14	O00487	1/20	0.45

▸	SPHK2	Q9NRA0	1/20	0.44

▸	SPHK1	Q9NYA1	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL6794537	0.92	ALDH1A1 (0.57)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL6794547	0.92	ALDH1A1 (0.57)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL7288562	0.91	ALDH1A1 (0.53)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL5741590	0.86	KMT2A (0.64)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL7290619	0.86	KMT2A (0.53)	KMT2AALDH1A1SMN1; SMN2CPT2CPT1A
SCHEMBL5741583	0.86	KMT2A (0.64)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL6787573	0.85	KMT2A (0.53)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL6787567	0.85	KMT2A (0.53)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL7290367	0.84	KMT2A (0.59)	KMT2AMEN1ALDH1A1SMN1; SMN2CPT2
SCHEMBL7297177	0.84	KMT2A (0.56)	KMT2AMEN1ALDH1A1CPT2CPT1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-0915088-B1	D-Proline derivatives	HOFFMANN LA ROCHE (CH)	2002-09-18	—	—	EP	claimed