Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7368022 | 0.89 | MEN1 (0.31) | — | |
| SCHEMBL7379309 | 0.89 | POLB (0.33) | POLBGAATSHR | |
| SCHEMBL7298549 | 0.86 | MAPT (0.34) | POLBGAATSHR | |
| SCHEMBL7288963 | 0.85 | NPC1 (0.33) | — | |
| SCHEMBL7377531 | 0.84 | POLB (0.38) | POLBGAATSHR | |
| SCHEMBL7373402 | 0.84 | S100A4 (0.32) | POLBGAATSHR | |
| SCHEMBL7299568 | 0.82 | POLB (0.34) | POLBGAATSHR | |
| SCHEMBL7298334 | 0.80 | TNKS (0.33) | — | |
| SCHEMBL7301120 | 0.78 | NR4A2 (0.31) | — | |
| SCHEMBL7299711 | 0.78 | WEE1 (0.31) | GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |