Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288576 | 0.89 | POLB (0.34) | — | |
| SCHEMBL7301120 | 0.87 | NR4A2 (0.31) | MAPT | |
| SCHEMBL7379309 | 0.85 | POLB (0.33) | — | |
| SCHEMBL7288963 | 0.83 | NPC1 (0.33) | MAPTRAB9A | |
| SCHEMBL7372112 | 0.83 | NPC1 (0.32) | MEN1MAPTHTTRAB9AKMT2A | |
| SCHEMBL7348702 | 0.82 | MEN1 (0.30) | MEN1MAPTHTTKMT2A | |
| SCHEMBL7373402 | 0.82 | S100A4 (0.32) | MEN1MAPTKMT2A | |
| SCHEMBL7299711 | 0.80 | WEE1 (0.31) | MAPTRAB9A | |
| SCHEMBL7374296 | 0.78 | CCNC (0.38) | — | |
| SCHEMBL7376009 | 0.78 | AURKA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |