Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7298334 | 0.89 | TNKS (0.33) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7368022 | 0.87 | MEN1 (0.31) | MAPT | |
| SCHEMBL7299711 | 0.85 | WEE1 (0.31) | MAPTSMN1; SMN2 | |
| SCHEMBL7300527 | 0.83 | TDP1 (0.33) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7300229 | 0.83 | NR4A2 (0.31) | NR4A2 | |
| SCHEMBL7348702 | 0.82 | MEN1 (0.30) | LMNAMAPT | |
| SCHEMBL7300381 | 0.82 | LMNA (0.31) | LMNAMAPTSMN1; SMN2 | |
| SCHEMBL7366868 | 0.82 | S100A4 (0.36) | LMNAMAPT | |
| SCHEMBL7379309 | 0.80 | POLB (0.33) | — | |
| SCHEMBL7289471 | 0.78 | CCNC (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0308792-B1 | AZACHROMANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1993-07-28 | — | — | EP | disclosed |
| US-4931454-A | Azachroman derivatives with effects on the cardiovascular system | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1990-06-05 | — | — | US | disclosed |
| EP-0308792-A2 | Azachromane derivatives | MERCK PATENT GmbH (DE) | 1989-03-29 | — | — | EP | disclosed |