Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTB4R | Q15722 | 1/20 | 0.48 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.48 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10697981 | 1.00 | LTB4R (0.48) | LTB4RLTB4R2HTR2BPOLBESR2 | |
| SCHEMBL10692134 | 0.79 | HTR1A (0.43) | HTR2BCYP3A4GRM7HTR1ASIGMAR1 | |
| SCHEMBL10692133 | 0.79 | HTR1A (0.43) | HTR2BCYP3A4GRM7HTR1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL10691714 | 0.78 | HTR1A (0.42) | HTR2BCYP3A4GRM7HTR1ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL10691710 | 0.78 | HTR1A (0.42) | HTR2BCYP3A4GRM7HTR1ASIGMAR1 | |
| SCHEMBL696876 | 0.75 | LTB4R (0.47) | LTB4RLTB4R2HTR2BPOLBHPGD | |
| SCHEMBL696877 | 0.75 | LTB4R (0.47) | LTB4RLTB4R2HTR2BPOLBHPGD | |
| SCHEMBL697337 | 0.75 | LTB4R (0.47) | LTB4RLTB4R2HTR2BPOLBHPGD | |
| SCHEMBL697338 | 0.75 | LTB4R (0.47) | LTB4RLTB4R2HTR2BPOLBHPGD | |
| SCHEMBL20182824 | 0.71 | LTB4R (0.56) | LTB4RLTB4R2POLBCYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0246633-B1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1991-01-02 | — | — | EP | disclosed |
| US-4792548-A | Trans-benzopyran-(4,3-b)-1,4-oxazine derivatives, intermediates and pharmaceutical use | WARNER-LAMBERT COMPANY (US) | 1988-12-20 | — | — | US | disclosed |
| EP-0246633-A1 | Trans-benzopyran-[4,3-b]-1,4-oxazine derivatives | WARNER-LAMBERT COMPANY (US) | 1987-11-25 | — | — | EP | disclosed |