SCHEMBL7288755

SCHEMBL7288755

O=C(NC(=NCCC(c1ccc(Cl)c(Cl)c1)c1ccccn1)NCCCc1c[nH]cn1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
S1PR3 Q99500 3/20 0.38
S1PR2 O95136 2/20 0.38
S1PR4 O95977 2/20 0.38
S1PR1 P21453 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9865155 0.92 BLM (0.40)
SCHEMBL7286314 0.91
SCHEMBL7303037 0.91 NPY1R (0.36)
SCHEMBL9865299 0.91 RAB9A (0.38)
SCHEMBL7312444 0.89 NPY1R (0.36)
SCHEMBL7283848 0.89 RAB9A (0.35)
SCHEMBL9865426 0.88 NAMPT (0.38)
SCHEMBL9865744 0.88 PMP22 (0.40)
SCHEMBL7311686 0.88 NPY1R (0.39)
SCHEMBL7296401 0.88 NPY1R (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0262448-A1 Imidazolylguanidine derivatives, process for their preparation and medicines containing them HEUMANN PHARMA GMBH & CO (DE) 1988-04-06 EP disclosed