Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7967174 | 0.90 | SLC6A4 (0.55) | SIGMAR1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL7289000 | 0.83 | SLC6A2 (0.57) | SIGMAR1SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL1977577 | 0.83 | SLC6A2 (0.57) | SIGMAR1SLC6A4SLC6A2HTR3EHTR3B | |
| SCHEMBL14035360 | 0.83 | GAA (0.65) | SIGMAR1MEN1KMT2ARAD52 | |
| SCHEMBL2797036 | 0.83 | GAA (0.65) | SIGMAR1MEN1KMT2ARAD52 | |
| SCHEMBL8305793 | 0.83 | ALDH1A1 (0.63) | SIGMAR1MEN1KMT2ASLC6A4SLC6A2 | |
| SCHEMBL14035242 | 0.83 | GAA (0.65) | SIGMAR1MEN1KMT2ARAD52 | |
| SCHEMBL24672687 | 0.82 | GAA (0.63) | SIGMAR1MEN1KMT2ARAD52 | |
| Hydrochloric Acid SCHEMBL4463437 | 0.82 | GAA (0.63) | SIGMAR1MEN1KMT2ARAD52 | |
| Hydrochloric Acid SCHEMBL3844155 | 0.82 | GAA (0.63) | SIGMAR1MEN1KMT2ARAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3007229-A | — | — | None | — | — | JP | disclosed |
| CN-106866555-B | 1- benzhydryl -4- methyl piperazine class compound preparation method and application | 东南大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-106866555-B | 1- benzhydryl -4- methyl piperazine class compound preparation method and application | 东南大学 | 2019-04-30 | — | — | CN | disclosed |
| CN-106866555-A | The methyl piperazine class compound its preparation method of 1 benzhydryl 4 and application | 东南大学 | 2017-06-20 | — | — | CN | disclosed |
| CN-106029060-A | piperidine and piperidine derivatives and their use in the treatment of viral infections and cancer | 美国卫生和人力服务部 | 2016-10-12 | — | — | CN | disclosed |
| EP-0691962-B1 | 1-AMINO-3-PHENOXY PROPANE DERIVATIVES AS MODULATORS OF MULTI-DRUG RESISTANCE | BASF AG (DE) | 2000-09-13 | — | — | EP | disclosed |
| US-5622953-A | DRUG RESISTANT TO ANTICANCER CHEMOTHERAPEUTIC DRUG | BASF AKTIENGESELLSCHAFT (DE) | 1997-04-22 | — | — | US | disclosed |
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |
| EP-0388081-B1 | Agent for the treatment of disorders of the cerebral neurotransmitter system | SANTEN PHARMACEUTICAL CO LTD (JP) | 1995-12-27 | — | — | EP | disclosed |
| US-5405843-A | Anticancer drug potentiators | MITSUI TOATSU CHEMICALS, INCORPORATED (JP) | 1995-04-11 | — | — | US | disclosed |
| EP-0388081-A2 | Agent for the treatment of disorders of the cerebral neurotransmitter system | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1990-09-19 | — | — | EP | disclosed |
| US-4935417-A | CALCIUM CHANNEL BLOCKERS | SYNTEX PHARMACEUTICALS LTD. (BM) | 1990-06-19 | — | — | US | disclosed |
| US-4933329-A | Bis-S-alkylbenzene derivatives | GREEN CROSS CORPORATION (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0363212-A2 | Novel heterocyclic compounds and anticancer-drug reinforcing agents containing them as effective components | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-04-11 | — | — | EP | disclosed |
| EP-0319947-A2 | Bis-S-alkylbenzene derivatives | GREEN CROSS CORPORATION (JP) | 1989-06-14 | — | — | EP | disclosed |
| US-4829065-A | Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1989-05-09 | — | — | US | disclosed |
| EP-0289227-A1 | Substituted imidazolyl-alkyl-piperazine and -diazepine derivatives | SYNTEX PHARMACEUTICALS LTD. (GB) | 1988-11-02 | — | — | EP | disclosed |
| US-4603135-A | HYPOTENSIVE AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1986-07-29 | — | — | US | disclosed |
| EP-0138505-A2 | Dihydropyridine derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1985-04-24 | — | — | EP | disclosed |
| US-4361562-A | CARDIOTONIC, ANTIARRHYTHMIC AND ADRENOCEPTOR BLOCKING AGENTS | SANDOZ LTD. (CH) | 1982-11-30 | — | — | US | disclosed |