Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 5/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7288783 | 0.90 | SIGMAR1 (0.56) | SLC6A4SIGMAR1SLC6A2SLC6A3MEN1 | |
| SCHEMBL6649269 | 0.79 | ADRB2 (0.44) | SLC6A4SIGMAR1SLC6A2ADRB2NCF1 | |
| SCHEMBL5549076 | 0.77 | MEN1 (0.79) | SLC6A4MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7289000 | 0.75 | SLC6A2 (0.57) | SLC6A4SIGMAR1SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL8305793 | 0.75 | ALDH1A1 (0.63) | SLC6A4SIGMAR1SLC6A2MEN1KMT2A | |
| SCHEMBL1977577 | 0.75 | SLC6A2 (0.57) | SLC6A4SIGMAR1SLC6A2SLC6A3CYP2D6 | |
| SCHEMBL14035360 | 0.75 | GAA (0.65) | SIGMAR1MEN1KMT2A | |
| SCHEMBL2797036 | 0.75 | GAA (0.65) | SIGMAR1MEN1KMT2A | |
| SCHEMBL14035242 | 0.75 | GAA (0.65) | SIGMAR1MEN1KMT2A | |
| SCHEMBL24672687 | 0.73 | GAA (0.63) | SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6172228-B1 | Process for producing piperazinesulfonamide derivatives and salts thereof | AZWELL INC. (JP) | 2001-01-09 | — | — | US | disclosed |