Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 5/20 | 0.61 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.61 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.60 |
| ▸ | FPR3 | P25089 | 1/20 | 0.60 |
| ▸ | GPR183 | P32249 | 1/20 | 0.60 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18983298 | 0.87 | NTSR1 (0.70) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL30741234 | 0.87 | NTSR1 (0.70) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL729311 | 0.86 | NTSR1 (0.73) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL727352 | 0.85 | APLNR (0.49) | NTSR1 | |
| SCHEMBL17114499 | 0.79 | NTSR1 (0.71) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| Methane SCHEMBL17114636 | 0.78 | NTSR1 (0.63) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL729743 | 0.77 | NTSR1 (0.70) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL8591555 | 0.76 | NTSR1 (0.69) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL729750 | 0.76 | NTSR1 (0.71) | NTSR1OPRM1OPRD1NTSR2FPR3 | |
| SCHEMBL17114586 | 0.76 | NTSR1 (0.74) | NTSR1OPRM1OPRD1NTSR2FPR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156557-A2 | COMPOUNDS ACTIVE AT THE NEUROTENSIN RECEPTOR | THOMAS JAMES B (US) | 2011-12-15 | — | — | WO | disclosed |