Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APLNR | P35414 | 8/20 | 0.49 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17114647 | 0.85 | APLNR (0.56) | APLNRNTSR1 | |
| SCHEMBL17114648 | 0.85 | APLNR (0.56) | APLNRNTSR1 | |
| SCHEMBL728944 | 0.85 | NTSR1 (0.61) | NTSR1 | |
| SCHEMBL727886 | 0.84 | NTSR1 (0.50) | APLNRPTGS2NTSR1 | |
| SCHEMBL17114580 | 0.78 | PTGS2 (0.51) | APLNRPTGS2NTSR1 | |
| SCHEMBL17114481 | 0.77 | APLNR (0.44) | APLNRPTGS2NTSR1 | |
| SCHEMBL8295919 | 0.75 | NTSR1 (0.59) | APLNRPTGS2NTSR1 | |
| SCHEMBL9083088 | 0.74 | APLNR (0.52) | APLNRNTSR1 | |
| SCHEMBL9086851 | 0.74 | APLNR (0.52) | APLNRNTSR1 | |
| SCHEMBL9084562 | 0.74 | APLNR (0.51) | APLNRNTSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011156557-A2 | COMPOUNDS ACTIVE AT THE NEUROTENSIN RECEPTOR | THOMAS JAMES B (US) | 2011-12-15 | — | — | WO | disclosed |