Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 3/20 | 0.50 |
| ▸ | CTSK | P43235 | 2/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 2/20 | 0.48 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9078755 | 0.90 | CTSB (0.57) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL9017588 | 0.90 | CTSB (0.57) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL20204825 | 0.90 | CTSB (0.57) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL1207885 | 0.88 | ATM (0.57) | ATMKLK5CTSSCTSKCTSL | |
| SCHEMBL5732519 | 0.88 | ATM (0.57) | ATMKLK5CTSSCTSKCTSL | |
| SCHEMBL13937947 | 0.88 | ATM (0.57) | ATMKLK5CTSSCTSKCTSL | |
| SCHEMBL29602242 | 0.82 | KMT2A (0.67) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL8130179 | 0.82 | KMT2A (0.67) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL8539393 | 0.82 | KLK5 (0.52) | ATMMEN1KMT2AKLK5CTSS | |
| SCHEMBL8542012 | 0.81 | CYP3A4 (0.59) | ATMMEN1KMT2AKLK5CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605926-A | PROPHYLAXIS | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-25 | — | — | US | disclosed |
| US-5430151-A | Treatment of aids, pneumonia, caprine arthritis encephalitis, leukemia and immmunodeficiency | BAYER AKTIENGESELLSCHAFT (DE) | 1995-07-04 | — | — | US | disclosed |
| US-5204471-A | α-trifluoromethyl-substituted, saturated bicyclic amines | BAYER AKTIENGESELLSCHAFT (DE) | 1993-04-20 | — | — | US | disclosed |
| EP-0528242-A2 | Trifluoromethyl containing pseudopeptides | BAYER AG (DE) | 1993-02-24 | — | — | EP | disclosed |
| EP-0472077-A2 | Phosphonate containing hydroxyethylamin- and norstatin-type pseudopeptides | BAYER AG (DE) | 1992-02-26 | — | — | EP | disclosed |