Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSB | P07858 | 3/20 | 0.57 |
| ▸ | ATM | Q13315 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 3/20 | 0.51 |
| ▸ | CTSK | P43235 | 2/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
| ▸ | BACE1 | P56817 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204825 | 1.00 | CTSB (0.57) | CTSBATMMEN1KMT2AKLK5 | |
| SCHEMBL9078755 | 1.00 | CTSB (0.57) | CTSBATMMEN1KMT2AKLK5 | |
| SCHEMBL8539393 | 0.90 | KLK5 (0.52) | CTSBATMMEN1KMT2AKLK5 | |
| SCHEMBL7289822 | 0.90 | ATM (0.52) | CTSBATMMEN1KMT2AKLK5 | |
| SCHEMBL390555 | 0.88 | ATM (0.62) | CTSBATMCTSSCTSKCTSL | |
| SCHEMBL7094 | 0.88 | ATM (0.62) | CTSBATMCTSSCTSKCTSL | |
| SCHEMBL1094506 | 0.88 | ATM (0.62) | CTSBATMCTSSCTSKCTSL | |
| SCHEMBL20204700 | 0.86 | CTSS (0.65) | CTSBATMCTSSCTSKCTSL | |
| SCHEMBL28269148 | 0.86 | CTSS (0.65) | CTSBATMCTSSCTSKCTSL | |
| SCHEMBL22962275 | 0.86 | CTSS (0.65) | CTSBATMCTSSCTSKCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0541946-B1 | Process for diastereo selective reductive pinacol-coupling of homochiral alpha-aminoaldehydes | HOECHST AG (DE) | 1996-07-17 | — | — | EP | disclosed |
| US-5519113-A | Process for the diastereoselective reductive pinacol coupling of homochiral α-aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-05-21 | — | — | US | disclosed |
| US-5463124-A | Treating with niobium trichloride-dimethoxyethane complex and simultaneously controlling all four corners of chirality | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| EP-0541946-A1 | Process for diastereo selective reductive pinacol-coupling of homochiral alpha-aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-05-19 | — | — | EP | disclosed |
| EP-0503561-A2 | Method for the diastereoselective reductive pinacol coupling of homochiral alpha aminoaldehydes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-09-16 | — | — | EP | disclosed |