Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 3/20 | 0.30 |
| ▸ | CTSL | P07711 | 2/20 | 0.30 |
| ▸ | CTSB | P07858 | 2/20 | 0.30 |
| ▸ | CTSH | P09668 | 2/20 | 0.30 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7297711 | 1.00 | CTSD (0.34) | CTSDCTSKCTSLCTSBCTSH | |
| SCHEMBL9417461 | 0.79 | KDM6B (0.32) | CTSD | |
| SCHEMBL8908550 | 0.79 | KDM6B (0.32) | CTSD | |
| SCHEMBL8908161 | 0.79 | KDM6B (0.32) | CTSD | |
| SCHEMBL9615179 | 0.74 | CTSD (0.37) | CTSD | |
| SCHEMBL8399697 | 0.73 | NAAA (0.34) | CTSDTDP1 | |
| SCHEMBL8399676 | 0.73 | NAAA (0.34) | CTSDTDP1 | |
| SCHEMBL7337078 | 0.73 | CTSD (0.35) | CTSD | |
| SCHEMBL7266630 | 0.72 | CTSD (0.33) | CTSD | |
| SCHEMBL7266627 | 0.72 | CTSD (0.33) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442044-A | Hypotensive agents | PFIZER INC. (US) | 1995-08-15 | — | — | US | disclosed |
| EP-0661292-A1 | Orally active renin inhibitors | PFIZER INC. (US) | 1995-07-05 | — | — | EP | disclosed |
| EP-0438233-A2 | Orally active renin inhibitors | PFIZER INC. (US) | 1991-07-24 | — | — | EP | disclosed |