Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 6/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KDM6B | O15054 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.31 |
| ▸ | KDM3B | Q7LBC6 | 1/20 | 0.31 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.30 |
| ▸ | REN | P00797 | 2/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8399697 | 1.00 | NAAA (0.34) | NAAACTSDNPC1RAB9AKDM6B | |
| SCHEMBL7290274 | 0.73 | CTSD (0.34) | CTSDTDP1 | |
| SCHEMBL7297711 | 0.73 | CTSD (0.34) | CTSDTDP1 | |
| SCHEMBL9615179 | 0.72 | CTSD (0.37) | CTSDMAPT | |
| SCHEMBL8908550 | 0.72 | KDM6B (0.32) | CTSDKDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL9417461 | 0.72 | KDM6B (0.32) | CTSDKDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL8908161 | 0.72 | KDM6B (0.32) | CTSDKDM6BKDM4AKDM4DKDM3B | |
| SCHEMBL7337078 | 0.71 | CTSD (0.35) | CTSD | |
| SCHEMBL7280255 | 0.69 | CTSD (0.33) | CTSD | |
| SCHEMBL7283590 | 0.69 | CTSD (0.33) | CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0771792-B1 | Process for the preparation of (4,5)-trans-oxazolidine derivatives | HOFFMANN LA ROCHE (CH) | 1999-06-02 | — | — | EP | disclosed |
| EP-0771792-A1 | Process for the preparation of (4,5)-trans-oxazolidine derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1997-05-07 | — | — | EP | disclosed |