SCHEMBL729029

SCHEMBL729029

CC(C(=O)c1ccccc1)N1C(=O)c2ccccc2C1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 1.00
ALDH1A1 P00352 4/20 0.54
HTT P42858 3/20 0.54
POLB P06746 1/20 0.54
NPC1 O15118 1/20 0.53
GAA P10253 1/20 0.51
KMT2A Q03164 1/20 0.51
SMN1; SMN2 Q16637 2/20 0.50
TSHR P16473 2/20 0.50
ALOX15 P16050 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
MAPT P10636 1/20 0.50
USP2 O75604 1/20 0.49
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12022720 1.00 LMNA (1.00) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL5390043 0.88 LMNA (0.79) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL5390032 0.88 LMNA (0.79) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL6957180 0.87 LMNA (0.77) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL10427299 0.84 LMNA (0.72) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL10427298 0.84 LMNA (0.72) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL29472125 0.83 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL125972 0.83 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL7399848 0.83 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1
SCHEMBL478339 0.83 LMNA (0.71) LMNAALDH1A1HTTPOLBNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200060997-A1 TARR Receptor Agonists for Sexual Dysfunction JOHN MCCOY 2020-02-27 US claimed
US-20160000815-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CT HOLDINGS PTY LTD (AU) 2016-01-07 US claimed
US-20140142140-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2014-05-22 US claimed
EP-2729216-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2014-05-14 EP claimed
WO-2013007698-A1 PHARMACEUTICAL COMPOSITION FOR NEUROLOGICAL DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2013-01-17 WO claimed
JP-2011529923-A 2011-12-15 JP claimed
US-20110207718-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD. (AU) 2011-08-25 US claimed
EP-2331088-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS Gosforth Centre (Holdings) Pty Ltd (AU) 2011-06-15 EP claimed
WO-2010015029-A1 COMPOSITIONS AND METHODS FOR TREATING PSYCHIATRIC DISORDERS GOSFORTH CENTRE (HOLDINGS) PTY LTD (AU) 2010-02-11 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO disclosed
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2026-02-12 US disclosed
EP-4079311-B1 NMN AND DERIVATIVES FOR USE IN THE TREATMENT OF DEPRESSION AND/OR ANXIETY IN PATIENTS HAVING A FORM OF PARKINSONISM NUVAMID SA (CH) 2025-10-01 EP disclosed
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism NUVAMID SA (CH) 2024-12-19 US disclosed
WO-2024118094-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INTERNATIONAL (US) 2024-06-06 WO disclosed
US-7247688-B2 Method for synthesis of block polymers by controlled free radical polymerization RHODIA CHIMIE (FR) 2007-07-24 US disclosed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US disclosed
US-20070027266-A1 Oxidizing one or more thiocarbonylthio ends of a polymer resulting from a radical polymerization controlled by reversible addition-fragmentation using thiocarbonylthio by reacting with ozone SPECIALTY OPERATIONS FRANCE (FR) 2007-02-01 US disclosed
US-6410749-B1 REACTING A CARBONYL COMPOUND WITH ORGANOMETALLIC COMPOUND NIPPON SODA CO., LTD. (JP) 2002-06-25 US disclosed
EP-1146037-A1 PROCESS FOR THE PREPARATION OF OPTICALLY ACTIVE AMINO ALCOHOLS NIPPON SODA CO., LTD. (JP) 2001-10-17 EP disclosed
US-3971772-A ANTINFLAMMATORY E. R. SQUIBB & SONS, INC. (US) 1976-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA DYRK4, DYRK2, STRA6 LMNA 2196/4885ALDH1A1 4003/4885HTT 125/4885
US-20240417421-A1 NMN And Derivatives For Its Use In The Treatment Of Depression And/Or Anxiety In Patients Having A Form Of Parkinsonism SNCA, NLN, PARK7 LMNA 173/4885ALDH1A1 1640/4885HTT 119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.