Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CPT2 | P23786 | 2/20 | 0.42 |
| ▸ | CPT1A | P50416 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MVD | P53602 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2503230 | 0.92 | KMT2A (0.67) | KMT2AL3MBTL1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL2503223 | 0.92 | KMT2A (0.67) | KMT2AL3MBTL1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL7290619 | 0.91 | KMT2A (0.53) | KMT2AALDH1A1PREPSMN1; SMN2CPT2 | |
| SCHEMBL5540038 | 0.88 | KMT2A (0.62) | KMT2AL3MBTL1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL7299218 | 0.84 | KMT2A (0.51) | KMT2AALDH1A1SMN1; SMN2CPT2CPT1A | |
| SCHEMBL7288562 | 0.84 | ALDH1A1 (0.53) | KMT2AL3MBTL1ALDH1A1SMN1; SMN2CPT2 | |
| SCHEMBL7985856 | 0.83 | KMT2A (0.57) | KMT2AL3MBTL1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL7985862 | 0.83 | KMT2A (0.57) | KMT2AL3MBTL1ALDH1A1PREPSMN1; SMN2 | |
| SCHEMBL2447301 | 0.82 | KMT2A (0.60) | KMT2AALDH1A1PREPSMN1; SMN2CPT2 | |
| SCHEMBL6789761 | 0.82 | KMT2A (0.60) | KMT2AALDH1A1PREPSMN1; SMN2CPT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0915088-B1 | D-Proline derivatives | HOFFMANN LA ROCHE (CH) | 2002-09-18 | — | — | EP | claimed |