SCHEMBL729227

SCHEMBL729227

CCCCCCCC(C(=O)O)n1ccnc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TBXAS1 P24557 10/20 0.47
TBXA2R P21731 1/20 0.46
CYP17A1 P05093 1/20 0.43
GPR84 Q9NQS5 3/20 0.42
FFAR1 O14842 1/20 0.42
MAPT P10636 1/20 0.41
LCK P06239 1/20 0.41
PPARD Q03181 1/20 0.41
ZDHHC20 Q5W0Z9 1/20 0.41
ZDHHC2 Q9UIJ5 1/20 0.41
AGTR1 P30556 1/20 0.41
AGTR2 P50052 1/20 0.41
CYP26A1 O43174 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5529653 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL3137862 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5538884 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5531361 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5531518 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5537297 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5538451 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5538578 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5533163 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1
SCHEMBL5535737 1.00 TBXAS1 (0.47) TBXAS1TBXA2RCYP17A1GPR84FFAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9040483-B2 Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor BIOVASCULAR, INC. (US) 2015-05-26 US claimed
US-20130022671-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. 2013-01-24 US claimed
JP-2011524416-A 2011-09-01 JP claimed
EP-2306985-A2 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR Biovascular, Inc. (US) 2011-04-13 EP claimed
WO-2010005480-A9 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. (US) 2010-05-27 WO claimed
WO-2010005480-A2 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. (US) 2010-01-14 WO claimed
US-20090324710-A1 Controlled release dosage forms for platelet inhibitor such as anagrelide, optionally in combination with other drugs; prevention of vaso-occlusive events, such as embolism BIOVASCULAR, INC. 2009-12-31 US claimed
US-20180153810-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR INC (US) 2018-06-07 US disclosed
US-9750698-B2 Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor BIOVASCULAR, INC. (US) 2017-09-05 US disclosed
US-9700521-B2 Multi-layered injectable self-assembling peptide scaffold hydrogels for long-term sustained release of human antibodies MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2017-07-11 US disclosed
US-20170112767-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. 2017-04-27 US disclosed
US-9381198-B2 Controlled release compositions of agents that reduce circulating levels of platelets and methods therefor BIOVASCULAR, INC. (US) 2016-07-05 US disclosed
US-20160051552-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. 2016-02-25 US disclosed
US-20130022671-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. 2013-01-24 US disclosed
EP-2306985-A2 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR Biovascular, Inc. (US) 2011-04-13 EP disclosed
WO-2010005480-A9 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. (US) 2010-05-27 WO disclosed
WO-2010005480-A2 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR BIOVASCULAR, INC. (US) 2010-01-14 WO disclosed
US-20090324710-A1 Controlled release dosage forms for platelet inhibitor such as anagrelide, optionally in combination with other drugs; prevention of vaso-occlusive events, such as embolism BIOVASCULAR, INC. 2009-12-31 US disclosed
US-20070044831-A1 Electrolyte composition and dye-sensitized solar cell NATIONAL UNIVERSITY CORPORATION KYUSHU INSTITUTE OF TECHNOLOGY (JP) 2007-03-01 US disclosed
US-4568676-A SYNERGISTIC INHIBITION THOMAS JEFFERSON UNIVERSITY (US) 1986-02-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324710-A1 Controlled release dosage forms for platelet inhibitor such as anagrelide, optionally in combination with other drugs; prevention of vaso-occlusive events, such as embolism PF4, PLAT, VASP TBXAS1 82/4885TBXA2R 16/4885CYP17A1 2545/4885
US-20130022671-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR SERPINC1, PLAT, MPL TBXAS1 42/4885TBXA2R 4/4885CYP17A1 2479/4885
US-20160051552-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR SERPINC1, PLAT, MPL TBXAS1 42/4885TBXA2R 4/4885CYP17A1 2479/4885
US-20180153810-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR SERPINC1, PLAT, MPL TBXAS1 42/4885TBXA2R 4/4885CYP17A1 2479/4885
US-20170112767-A1 CONTROLLED RELEASE COMPOSITIONS OF AGENTS THAT REDUCE CIRCULATING LEVELS OF PLATELETS AND METHODS THEREFOR SERPINC1, PLAT, MPL TBXAS1 42/4885TBXA2R 4/4885CYP17A1 2479/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.