Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
| ▸ | GABBR2 | O75899 | 2/20 | 0.53 |
| ▸ | GABBR1 | Q9UBS5 | 2/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | EDNRB | P24530 | 1/20 | 0.46 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148756 | 0.88 | TRPA1 (0.48) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL8099915 | 0.86 | CYP1A2 (0.47) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL1059563 | 0.85 | CYP2D6 (0.56) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL8192677 | 0.85 | CYP2D6 (0.56) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| SCHEMBL8187229 | 0.85 | CYP2D6 (0.56) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| Malonic Acid SCHEMBL18006516 | 0.84 | GABBR2 (0.52) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| Felbamate SCHEMBL1049127 | 0.83 | CYP1A2 (0.86) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| Benzoic Acid SCHEMBL14955665 | 0.83 | TSHR (0.58) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| Phosphonic Acid SCHEMBL29019105 | 0.82 | GSR (0.44) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 | |
| Boric Acid SCHEMBL21356833 | 0.81 | TRPA1 (0.43) | CYP2D6CYP1A2PKMSMN1; SMN2NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0491094-B1 | Felbamate for treating Lennox-Gastaut syndrome | CARTER WALLACE (US) | 1996-09-11 | — | — | EP | claimed |
| EP-0491094-A1 | Felbamate for treating Lennox-Gastaut syndrome | CARTER-WALLACE, INC. (US) | 1992-06-24 | — | — | EP | claimed |